Tonight in Canton, Ohio, the Detroit Lions and Los Angeles Chargers will begin the 2025-26 NFL preseason with the Hall of Fame Game. Anyone wanting to lay some action on the game can do so at any 18-friendly NFL sportsbook that we recommend here, and the Lions are favored by a point in most cases.
Once the opening two offensive drives wrap up for the Lions and Chargers and the reality that no starters are involved sets in, the focus will begin to shift to what this season will hold for all 32 franchises.
Here are four questions that are dominating the NFL betting landscape entering the 2025-26 regular season.
Will the Buffalo Bills finally win the Super Bowl?
After several close calls and playoff heartbreaks, many expect the Bills with MVP Josh Allen to break through this season and finally get the Super Bowl monkey off their back. Many NFL sportsbooks have the Bills leading the odds to win it all, but some feature the Baltimore Ravens at the top of the list.
Is this the year that Buffalo gets past Kansas City in the postseason? Current AFC futures suggest that they will, and Allen is a top contender to become the league’s MVP.
Regular Season NFL MVP Odds
- Lamar Jackson (BAL)+500
- Josh Allen (BUF)+565
- Joe Burrow (CIN)+600
- Patrick Mahomes (KC)+600
- Jayden Daniels (WAS)+850
- Jordan Love (GB)+2000
- Justin Herbert (LAC)+2000
- Brock Purdy (SF)+2200
- C.J. Stroud (HOU)+2500
Can the Philadelphia Eagles repeat as champions?
The Eagles are rated as the most likely team to win the NFC and return to the Super Bowl. The Bills and Ravens odds to win SB 60 are slightly above the Eagles, suggesting that Philadelphia will come one win short of a repeat.
If the Eagles can make it to the big game with a fully healthy Saquon Barkley once again, it’ll be difficult to bet against them.
Super Bowl LX Odds To Win
- Baltimore Ravens +600
- Buffalo Bills +625
- Philadelphia Eagles +750
- Kansas City Chiefs +800
- Detroit Lions +1100
- Los Angeles Rams +1600
- San Francisco 49ers +1600
- Washington Commanders +2000
- Cincinnati Bengals +2200
What Will Be The Impact Of Travis Hunter On The Jaguars?
Travis Hunter is expected to have a significant impact on the Jacksonville Jaguars as a rare two-way player in the NFL, contributing both as a wide receiver and a cornerback.
The Jaguars traded up to select him second overall in the 2025 draft, signaling their belief in his transformational potential. Head coach Liam Coen plans to integrate Hunter by alternating him between offense and defense during practices and games, carefully managing his workload to maximize his effectiveness and health.
Hunter’s versatility could boost the Jaguars’ offense with elite playmaking alongside receiver Brian Thomas Jr., and also strengthen a struggling secondary. However, his full-time two-way role remains a challenge, with the team gradually increasing his snaps on both sides.
Is Cam Ward For Real?
Rookie QB Cam Ward is prepared to start the season as the starter for the Tennessee Titans and is rated as the second-overall potential winner of the NFL OPOY award.
Offensive Rookie of the Year Odds
- Ashton Jeanty (LVR)+225
- Cameron Ward+325
- Tyler Shough (NO)+900
- Omarion Hampton (LAC)+1000
- Travis Hunter (JAX)+1000
- Tetairoa McMillan (CAR)+1100
- R.J. Harvey+2200
- Colston Loveland (NO)+2500
- Matthew Golden (GB)+2500
Ward possesses elite passing skills and athletic talent, but his statistical output will be tempered due to his surrounding cast. Look for his impact to be felt more in the win-loss column than on the stat sheet.
